Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 9/20 | 0.49 |
| ▸ | BCR | P11274 | 6/20 | 0.49 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25755088 | 0.80 | KIF11 (0.56) | ABL1BCRADORA3KDM2BKDM4C | |
| SCHEMBL6180227 | 0.80 | SCN10A (0.58) | SCN10AABL1BCRMAT2AADORA3 | |
| SCHEMBL21022111 | 0.78 | TGFBR1 (0.48) | KDM4ENPC1ALDH1A1GAARAB9A | |
| SCHEMBL10163809 | 0.78 | SCN10A (0.50) | SCN10AABL1BCRMAT2ASMO | |
| SCHEMBL25002931 | 0.76 | SCN10A (0.67) | SCN10AABL1BCRMAT2AADORA3 | |
| SCHEMBL18696372 | 0.76 | ABL1 (0.76) | ABL1BCRKDM4EMAPT | |
| SCHEMBL20582574 | 0.76 | KIF11 (0.62) | CHRNA7KIF11KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28074538 | 0.75 | ABL1 (0.61) | ABL1BCRADORA3KDM4EMAPT | |
| SCHEMBL28043073 | 0.75 | SCN5A (0.46) | SCN10AABL1BCRCHRNA7ADORA3 | |
| SCHEMBL26739795 | 0.74 | ASIC3 (0.53) | SMOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |