Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 20/20 | 1.00 |
| ▸ | RORC | P51449 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257608 | 0.89 | RORB (0.83) | RORBRORC | |
| SCHEMBL257434 | 0.88 | RORB (0.79) | RORBRORC | |
| SCHEMBL257271 | 0.86 | RORB (0.76) | RORBRORC | |
| SCHEMBL257437 | 0.86 | RORB (0.76) | RORBRORC | |
| SCHEMBL174906 | 0.85 | RORB (0.74) | RORBRORC | |
| SCHEMBL257142 | 0.85 | RORB (1.00) | RORBRORC | |
| SCHEMBL257432 | 0.85 | RORB (0.74) | RORBRORC | |
| SCHEMBL257615 | 0.84 | RORB (0.72) | RORBRORC | |
| SCHEMBL10092885 | 0.82 | RORB (0.70) | RORBRORC | |
| SCHEMBL2493975 | 0.82 | RORB (0.69) | RORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |