Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 19/20 | 0.74 |
| ▸ | RORC | P51449 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257572 | 0.85 | RORB (1.00) | RORBRORC | |
| SCHEMBL175512 | 0.84 | RORB (0.54) | RORBRORCADORA2AADORA1 | |
| SCHEMBL257608 | 0.84 | RORB (0.83) | RORBRORC | |
| SCHEMBL257271 | 0.81 | RORB (0.76) | RORBRORC | |
| SCHEMBL257142 | 0.80 | RORB (1.00) | RORBRORC | |
| SCHEMBL257437 | 0.79 | RORB (0.76) | RORBRORC | |
| SCHEMBL257434 | 0.76 | RORB (0.79) | RORBRORC | |
| SCHEMBL257203 | 0.76 | RORB (0.67) | RORBRORC | |
| SCHEMBL6288104 | 0.75 | ALDH1A1 (0.69) | ADORA2A | |
| SCHEMBL175295 | 0.74 | RORB (0.67) | RORBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |