Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 15/20 | 0.76 |
| ▸ | RORC | P51449 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257608 | 0.92 | RORB (0.83) | RORBRORCPOLBALDH1A1MAPT | |
| SCHEMBL256653 | 0.87 | RORB (0.59) | RORBRORCPOLBALDH1A1MEN1 | |
| SCHEMBL257572 | 0.86 | RORB (1.00) | RORBRORC | |
| SCHEMBL178218 | 0.84 | ADORA3 (0.60) | RORBRORCPOLBALDH1A1MEN1 | |
| SCHEMBL257203 | 0.84 | RORB (0.67) | RORBRORCPOLBALDH1A1RECQL | |
| SCHEMBL257438 | 0.82 | ADORA3 (0.54) | RORBRORCPOLBALDH1A1MEN1 | |
| SCHEMBL257616 | 0.81 | ADORA3 (0.64) | RORBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL257271 | 0.80 | RORB (0.76) | RORBRORCPOLBKMT2A | |
| SCHEMBL174906 | 0.79 | RORB (0.74) | RORBRORC | |
| SCHEMBL257142 | 0.79 | RORB (1.00) | RORBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |