Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450334 | 0.84 | HTT (0.73) | HTTPRCPDRD2DRD4DRD3 | |
| SCHEMBL25760663 | 0.76 | NPC1 (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL25760660 | 0.74 | NPC1 (0.41) | HTTPRCPDRD2DRD1DRD4 | |
| SCHEMBL24112340 | 0.73 | DRD2 (0.55) | HTTPRCPSLC18A3DRD2DRD4 | |
| SCHEMBL20005705 | 0.73 | RAB9A (0.60) | HTTALDH1A1GAAKMT2A | |
| SCHEMBL17788490 | 0.73 | CARM1 (0.60) | PRCPSLC18A3DRD2DRD1DRD4 | |
| SCHEMBL12209849 | 0.73 | ALDH1A1 (0.60) | HTTSLC18A3DRD2ALDH1A1LMNA | |
| SCHEMBL23374659 | 0.73 | SLC18A3 (0.56) | SLC18A3DRD2DRD1DRD4DRD5 | |
| SCHEMBL12447397 | 0.73 | SLC18A3 (0.56) | SLC18A3DRD2DRD1DRD4DRD5 | |
| SCHEMBL12768109 | 0.73 | SLC18A3 (0.56) | SLC18A3DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | HTT 2737/4885PRCP 11/4885SLC18A3 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.