SCHEMBL25765617

SCHEMBL25765617

CC(C)c1ccc2c(c1)c1cc(C(C)C)ccc1n2C(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CASR P41180 11/20 0.44
RORA P35398 1/20 0.43
RORC P51449 1/20 0.43
RORB Q92753 1/20 0.43
LMNA P02545 1/20 0.40
TRPA1 O75762 1/20 0.39
PTGS1 P23219 1/20 0.39
CACNA1C Q13936 1/20 0.39
NPY5R Q15761 1/20 0.39
DHFR P00374 1/20 0.38
SLC2A1 P11166 1/20 0.38
PARP15 Q460N3 1/20 0.38
PARP10 Q53GL7 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25765615 0.90 MEN1 (0.58) MEN1KMT2ACASRRORARORC
SCHEMBL19543368 0.82 KIF11 (0.41) MEN1KMT2ACASRLMNATRPA1
SCHEMBL12083594 0.82 RORA (0.46) MEN1KMT2ACASRRORARORC
SCHEMBL26398797 0.80 RORA (0.42) CASRRORARORCRORBLMNA
SCHEMBL13338392 0.77 MEN1 (0.45) MEN1KMT2ARORARORCRORB
SCHEMBL13084772 0.77 RORC (0.54) MEN1KMT2ARORARORCRORB
SCHEMBL24667858 0.76 MEN1 (0.48) MEN1KMT2ACASRRORARORC
SCHEMBL29411034 0.76 KDM4E (0.46) MEN1KMT2ARORARORCRORB
SCHEMBL28847048 0.76 KDM4E (0.46) MEN1KMT2ARORARORCRORB
SCHEMBL14752432 0.76 DNM1 (0.44) MEN1KMT2ALMNANPY5RDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CRY2, NR2E3 MEN1 1665/4885KMT2A 1798/4885CASR 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.