Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061184 | 0.85 | HTR7 (0.47) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL23861171 | 0.85 | HTR7 (0.47) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL29975085 | 0.75 | HTR7 (0.56) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL23579204 | 0.75 | HTR7 (0.56) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL25784105 | 0.75 | CHRNB2 (0.44) | HTR7HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL11448408 | 0.73 | HRH3 (0.56) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL24344353 | 0.71 | ALOX5AP (0.39) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23861109 | 0.71 | CHRNB2 (0.46) | HTR7HRH3KEAP1NFE2L2KDM4E | |
| SCHEMBL29888806 | 0.70 | KDM4E (0.67) | HTR7HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL1811126 | 0.70 | KDM4E (0.49) | HTR7HRH3KEAP1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | HTR7 2208/4885HRH3 4248/4885KEAP1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.