Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579204 | 1.00 | HTR7 (0.56) | HTR7ALDH1A1KEAP1NFE2L2KDM4E | |
| SCHEMBL8068646 | 0.80 | KDM4E (0.49) | HTR7ALDH1A1KEAP1NFE2L2KDM4E | |
| SCHEMBL30061184 | 0.80 | HTR7 (0.47) | HTR7ALDH1A1KEAP1NFE2L2KDM4E | |
| SCHEMBL23861171 | 0.80 | HTR7 (0.47) | HTR7ALDH1A1KEAP1NFE2L2KDM4E | |
| SCHEMBL6712545 | 0.79 | ALDH1A1 (0.66) | HTR7ALDH1A1KEAP1NFE2L2HTR1B | |
| SCHEMBL28207980 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4E | |
| SCHEMBL25784108 | 0.75 | HTR7 (0.46) | HTR7ALDH1A1KEAP1NFE2L2KDM4E | |
| SCHEMBL29972937 | 0.74 | CHRNB2 (0.51) | HTR7ALDH1A1KDM4ELMNACHRNB2 | |
| SCHEMBL23609423 | 0.74 | CHRNB2 (0.51) | HTR7ALDH1A1KDM4ELMNACHRNB2 | |
| SCHEMBL11448408 | 0.74 | HRH3 (0.56) | HTR7ALDH1A1KEAP1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |