SCHEMBL25791676

SCHEMBL25791676

CCCCCC(=O)NCCOCCOCCOCCOCc1cn(C(C)C)nn1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.39
CNR2 P34972 2/20 0.39
GLP1R P43220 8/20 0.38
DGAT1 O75907 4/20 0.37
FAAH O00519 2/20 0.36
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25791661 0.85 P2RX7 (0.34) DGAT1P2RX7
SCHEMBL24812536 0.84 GLA (0.37) DGAT1
SCHEMBL6726642 0.77 MMP2 (0.43) CNR1CNR2DGAT1
SCHEMBL22473656 0.77 ZDHHC20 (0.49) DGAT1
SCHEMBL21118389 0.76 DGAT1 (0.47) DGAT1
SCHEMBL27371572 0.75 CYP19A1 (0.35) DGAT1
SCHEMBL19286590 0.75 LMNA (0.40) DGAT1
SCHEMBL26011534 0.74 KMT2A (0.39) CNR1
SCHEMBL7650140 0.73 FAAH (0.62) GLP1RFAAH
SCHEMBL13811075 0.73 FAAH (0.62) GLP1RFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122298-A1 PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS Stablix, Inc. (US) 2023-06-29 WO disclosed