Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809918 | 0.80 | KDM1A (0.66) | KDM1AUSP28 | |
| SCHEMBL25794232 | 0.78 | USP28 (0.50) | KDM1AALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL25795474 | 0.73 | USP28 (0.68) | KDM1AUSP28 | |
| SCHEMBL25795472 | 0.73 | USP28 (0.83) | KDM1AUSP28 | |
| SCHEMBL25809849 | 0.71 | USP28 (0.69) | KDM1AALDH1A1LMNACNR2TSHR | |
| SCHEMBL16554506 | 0.68 | CNR2 (1.00) | CNR2 | |
| SCHEMBL25794195 | 0.67 | USP28 (0.81) | KDM1AALDH1A1LMNAUSP28 | |
| SCHEMBL31550412 | 0.67 | ALDH1A1 (0.58) | ALDH1A1NPSR1LMNASMN1; SMN2CNR2 | |
| SCHEMBL16555115 | 0.64 | CNR2 (1.00) | CNR2 | |
| SCHEMBL25827780 | 0.64 | USP28 (0.85) | KDM1AUSP28 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |