SCHEMBL2580305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2580309	0.88	TSHR (0.36)	MAPTMEN1KMT2AHTR1ASMN1; SMN2
	SCHEMBL2582058	0.86	FFAR4 (0.46)	MEN1KMT2AFFAR1FFAR4HPGD
	SCHEMBL2588036	0.84	MET (0.40)	MAPTMEN1KMT2AFFAR1FFAR4
	SCHEMBL2578819	0.81	PDE4A (0.42)	MAPTSMN1; SMN2METKDRPDE4A
	SCHEMBL1136220	0.77	HTR1A (0.39)	MAPTKMT2AHTR1AHTR7SMN1; SMN2
	SCHEMBL2588063	0.74	ALDH1A1 (0.44)	KMT2ACYP2D6METKDRACHE
	SCHEMBL12160556	0.72	POLB (0.53)	MEN1KMT2AHTR1ADRD2HTR7
	Hydrochloric Acid SCHEMBL2580298	0.72	POLB (0.54)	MEN1KMT2AHTR1ADRD2HTR7
	SCHEMBL2588182	0.72	FFAR4 (0.52)	FFAR1FFAR4METKDR
	SCHEMBL2588042	0.71	TSHR (0.39)	KMT2ACYP2D6CYP2C19FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.