SCHEMBL2582058

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2580305	0.86	MAPT (0.37)	FFAR4FFAR1HPGDKMT2AMEN1
	SCHEMBL2580309	0.82	TSHR (0.36)	HPGDKMT2AMEN1ALDH1A1
	SCHEMBL1136220	0.81	HTR1A (0.39)	HPGDKMT2AALDH1A1HTTPRKAB2
	SCHEMBL2575829	0.77	FFAR4 (0.46)	FFAR4FFAR1PRKAB2PRKAG1PRKAA2
	SCHEMBL14479018	0.74	FFAR1 (0.43)	FFAR4FFAR1PRKAB2PRKAG1PRKAA2
	SCHEMBL2434369	0.70	HTR1A (0.40)	KMT2AALDH1A1HTT
	SCHEMBL2586505	0.69	FFAR1 (0.41)	FFAR4FFAR1CYP2C9RAB9A
	SCHEMBL2492033	0.68	MET (0.41)	FFAR4FFAR1RAB9AHTTPRKAB2
	SCHEMBL1135945	0.68	CPS1 (0.48)	HPGDRAB9AALDH1A1HTTNPSR1
	SCHEMBL2584922	0.68	PTGDR2 (0.50)	FFAR1ALDH1A1PRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.