Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21628078 | 0.82 | REN (0.56) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2580428 | 0.80 | ALDH1A1 (0.41) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4207867 | 0.79 | HDAC1 (0.57) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1753870 | 0.77 | HDAC6 (0.58) | RENLMNACNR2HDAC1HDAC6 | |
| SCHEMBL5506263 | 0.77 | REN (0.51) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL671194 | 0.77 | REN (0.55) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2584582 | 0.77 | LIMK2 (0.56) | RENMEN1KMT2ATDP1 | |
| SCHEMBL901839 | 0.76 | REN (0.50) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16333819 | 0.76 | REN (0.54) | RENMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11208970 | 0.76 | REN (0.50) | RENMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563847-B1 | MCR DENDRIMERS | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2563847-A1 | MCR DENDRIMERS | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134607-A1 | MCR DENDRIMERS | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (DE) | 2011-11-03 | — | — | WO | disclosed |