Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATF4 | P18848 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25797055 | 0.93 | PABPC1 (0.47) | RXFP1RECQLARTHRBPABPC1 | |
| SCHEMBL19568288 | 0.93 | PABPC1 (0.47) | RXFP1RECQLARTHRBPABPC1 | |
| SCHEMBL25812808 | 0.88 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1GAAATF4 | |
| SCHEMBL20992354 | 0.84 | RXFP1 (0.47) | RXFP1RECQLARTHRBKMT2A | |
| SCHEMBL19556241 | 0.84 | ATF4 (0.52) | RXFP1RECQLTHRBKMT2AMEN1 | |
| SCHEMBL25796964 | 0.83 | ATF4 (0.40) | ALDH1A1GAAATF4 | |
| SCHEMBL25813024 | 0.83 | ATF4 (0.40) | ALDH1A1GAAATF4 | |
| SCHEMBL19568855 | 0.83 | ATF4 (0.43) | KMT2AMEN1ALDH1A1ATF4 | |
| SCHEMBL19568400 | 0.82 | SSTR3 (0.44) | KMT2AMEN1ALDH1A1GAAATF4 | |
| SCHEMBL25797066 | 0.80 | ALDH1A1 (0.37) | ALDH1A1GAAATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |