Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 5/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809331 | 0.84 | CYP2D6 (0.64) | CYP3A4CYP2D6TSHR | |
| SCHEMBL25809385 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP2D6TSHRFAAH | |
| SCHEMBL16117809 | 0.82 | GPR183 (0.65) | GPR183OPRK1FAAH | |
| SCHEMBL25809447 | 0.82 | CYP3A4 (0.65) | CYP3A4CYP2D6TSHR | |
| SCHEMBL20556708 | 0.80 | ERN1 (0.56) | GPR183ERN1CYP3A4CYP2D6TSHR | |
| SCHEMBL25809381 | 0.80 | CYP3A4 (0.50) | CYP3A4CYP2D6TSHR | |
| SCHEMBL25809438 | 0.80 | ALDH1A1 (0.52) | CYP3A4CYP2D6TSHRMGLL | |
| SCHEMBL21393286 | 0.79 | CYP2D6 (0.68) | CYP3A4CYP2D6TSHR | |
| SCHEMBL25809445 | 0.78 | DOCK5 (0.49) | GPR183CYP3A4CYP2D6TSHR | |
| SCHEMBL21257978 | 0.78 | ERN1 (0.51) | GPR183ERN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |