Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809438 | 0.82 | ALDH1A1 (0.52) | CYP3A4CYP2D6ALDH1A1TSHRCYP1A2 | |
| SCHEMBL25809331 | 0.82 | CYP2D6 (0.64) | CYP3A4CYP2D6ALDH1A1TSHRHPGD | |
| SCHEMBL25809393 | 0.82 | CYP3A4 (0.45) | CYP3A4CYP2D6ALDH1A1TSHRHPGD | |
| SCHEMBL25809447 | 0.80 | CYP3A4 (0.65) | CYP3A4CYP2D6ALDH1A1TSHRHPGD | |
| SCHEMBL25809441 | 0.80 | GPR183 (0.58) | CYP3A4CYP2D6TSHR | |
| SCHEMBL25809445 | 0.79 | DOCK5 (0.49) | CYP3A4CYP2D6ALDH1A1TSHRHPGD | |
| SCHEMBL21393286 | 0.77 | CYP2D6 (0.68) | CYP3A4CYP2D6ALDH1A1TSHRHPGD | |
| SCHEMBL25809385 | 0.76 | CYP3A4 (0.48) | CYP3A4CYP2D6TSHRCYP1A2USP2 | |
| SCHEMBL25809456 | 0.76 | CYP2D6 (0.63) | CYP3A4CYP2D6ALDH1A1TSHRUSP2 | |
| SCHEMBL25809390 | 0.76 | CYP3A4 (0.46) | CYP3A4CYP2D6ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |