Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809331 | 0.81 | CYP2D6 (0.64) | CYP2D6TSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL25809385 | 0.80 | CYP3A4 (0.48) | FAAHCYP2D6KMT2AOPRL1TSHR | |
| SCHEMBL25809389 | 0.76 | ALDH1A1 (0.48) | CYP2D6KMT2AMGLLTSHRCYP3A4 | |
| SCHEMBL21393286 | 0.75 | CYP2D6 (0.68) | CYP2D6TSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL25809450 | 0.74 | CYP2D6 (0.51) | CYP2D6MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL25809456 | 0.74 | CYP2D6 (0.63) | CYP2D6TSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL25809447 | 0.74 | CYP3A4 (0.65) | CYP2D6MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL25809386 | 0.73 | CHRM2 (0.54) | FAAHCYP2D6TSHRCYP3A4CYP2C19 | |
| SCHEMBL25809390 | 0.72 | CYP3A4 (0.46) | CYP2D6TSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL16673587 | 0.71 | FAAH (0.71) | FAAHMEN1KMT2AMGLLHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |