SCHEMBL2581218

SCHEMBL2581218

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nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
PTGS2 P35354 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PTGS1 P23219 1/20 0.42
GSTK1 Q9Y2Q3 1/20 0.42
ECE1 P42892 1/20 0.42
MME P08473 5/20 0.41
ACE P12821 2/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
GLO1 Q04760 1/20 0.37
LTA4H P09960 2/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582106 1.00 ALDH1A1 (0.48) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL12161295 1.00 ALDH1A1 (0.48) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL29351388 0.92 ALDH1A1 (0.42) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL24709575 0.87 SLC22A6 (0.37) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL3451522 0.87 ALDH1A1 (0.45) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL16685 0.87 ALDH1A1 (0.45) ALDH1A1LMNAMAPTPTGS2TDP1
Hydroxyamine SCHEMBL8490496 0.85 ALDH1A1 (0.44) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL22315777 0.84 PTGS1 (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL29579224 0.84 PTGS1 (0.50) ALDH1A1LMNAMAPTPTGS2TDP1
Glycine SCHEMBL1694000 0.82 ALDH1A1 (0.41) ALDH1A1LMNAMAPTPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074042-A Histamine H1 receptor antagonistic composition 株式会社明治 2026-05-22 CN claimed
EP-4605407-A2 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS Endevica Bio, Inc. (US) 2025-08-27 EP claimed
CN-119219738-A Alternaria sinica antihypertensive peptide as well as preparation method and application thereof 湘潭大学 2024-12-31 CN claimed
CN-118873503-A Oral flash-disintegrating tablet of pet milk calcium and preparation method and application thereof 济南广盛源生物科技有限公司 2024-11-01 CN claimed
CN-118376786-A Urine metabolism marker for colorectal cancer detection and application thereof 哈尔滨脉图精准技术有限公司 2024-07-23 CN claimed
WO-2024086381-A2 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO, INC. (US) 2024-04-25 WO claimed
CN-116870184-A Self-assembled material for improving atherosclerosis as well as preparation method and application thereof 国家纳米科学中心 2023-10-13 CN claimed
US-20230272100-A1 ANTIBODIES AGAINST OX-40 AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2023-08-31 US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-112852905-B Application of dipeptide in improving paramylon content in euglena 优格天成生物技术(义乌)有限公司 2023-06-23 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-2207525-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT METHOD L'Oréal (FR) 2010-07-21 EP claimed
EP-2205201-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'Oreal (FR) 2010-07-14 EP claimed
WO-2009053594-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
WO-2009053584-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
WO-2009053587-A2 COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
EP-2021353-A2 PEPTIDE SUBSTANCE REVEALING A STRESS PROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION ON ITS BASE AND THE METHOD OF ITS APPLICATION Obschestvo S Ogranichennoi Otvetstvennostyu "sia Peptides" (RU) 2009-02-11 EP claimed
WO-2007136295-A2 PEPTIDE SUBSTANCE REVEALING A STRESS PROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION ON ITS BASE AND THE METHOD OF ITS APPLICATION OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU 'SIA PEPTIDES' (RU) 2007-11-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272100-A1 ANTIBODIES AGAINST OX-40 AND USES THEREOF IGLV6-57, CD47, IGSF11 ALDH1A1 2739/4885LMNA 4598/4885MAPT 3673/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALDH1A1 1901/4885LMNA 1561/4885MAPT 2575/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALDH1A1 1510/4885LMNA 833/4885MAPT 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.