Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818082 | 0.92 | DDB1 (0.47) | DDB1CRBNHTR1AHTR7DRD2 | |
| SCHEMBL25818076 | 0.87 | DDB1 (0.52) | DDB1CRBNMEN1KMT2AKDM4E | |
| SCHEMBL31586109 | 0.84 | DDB1 (0.50) | DDB1CRBNHTR1AHTR7DRD2 | |
| SCHEMBL31587053 | 0.82 | HTR1A (0.48) | DDB1CRBNHTR1AHTR7LMNA | |
| SCHEMBL31586422 | 0.82 | HTR1A (0.48) | DDB1CRBNHTR1AHTR7LMNA | |
| SCHEMBL25035204 | 0.81 | HTR7 (0.50) | DDB1CRBNHTR1AHTR7ALDH1A1 | |
| SCHEMBL25634636 | 0.80 | CRBN (0.63) | DDB1CRBNKMT2ALMNAGAA | |
| SCHEMBL30678689 | 0.80 | DDB1 (0.56) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL27197476 | 0.80 | DDB1 (0.56) | DDB1CRBNHTR1ADRD2DRD4 | |
| SCHEMBL27197516 | 0.79 | LMNA (0.47) | DDB1CRBNMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |