Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1077457 | 1.00 | FABP3 (0.39) | FABP3HMGCRFAAHALOX5 | |
| Potassium Ion SCHEMBL1077762 | 1.00 | FABP3 (0.39) | FABP3HMGCRFAAHALOX5 | |
| SCHEMBL2585837 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL2591807 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL14735313 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL2585839 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL1047023 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL2587903 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL11894515 | 0.88 | HMGCR (0.43) | FABP3HMGCR | |
| SCHEMBL2591804 | 0.88 | HMGCR (0.43) | FABP3HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134538-A1 | DIYNE COMPOSITIONS | EVOLVA LTD (CH) | 2011-11-03 | — | — | WO | disclosed |