Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819220 | 0.92 | GLS (0.37) | GLSRORCKDM4EMAPTPDE4D | |
| SCHEMBL25260616 | 0.92 | RORC (0.37) | GLSADORA2BRORCKDM4EMAPT | |
| SCHEMBL31270748 | 0.85 | ADORA2B (0.41) | GLSADORA2BRORCCHEK2GPR119 | |
| SCHEMBL25262168 | 0.85 | ADORA2B (0.41) | GLSADORA2BRORCCHEK2GPR119 | |
| SCHEMBL25301552 | 0.83 | RORC (0.37) | GLSRORCKDM4EMAPTGPR119 | |
| SCHEMBL25818360 | 0.81 | TLR7 (0.36) | P2RX3 | |
| SCHEMBL25294832 | 0.79 | ADORA2B (0.40) | GLSADORA2BRORCKDM4EMAPT | |
| SCHEMBL31270807 | 0.79 | ADORA2B (0.40) | GLSADORA2BRORCKDM4EMAPT | |
| SCHEMBL25303740 | 0.79 | P2RX3 (0.43) | P2RX3LMNAFAAHMEN1KMT2A | |
| SCHEMBL31270623 | 0.78 | GLS (0.39) | GLSRORCGPR119LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |