Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661514 | 0.69 | — | — | |
| SCHEMBL25297193 | 0.69 | SLC6A9 (0.34) | POLBALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL24164181 | 0.67 | CHRM2 (0.38) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL16548495 | 0.66 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL8127649 | 0.65 | HPGD (0.42) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL15448627 | 0.63 | NPC1 (0.49) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL23879771 | 0.63 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL10000241 | 0.63 | NPC1 (0.49) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB | |
| SCHEMBL12319410 | 0.62 | CHRM2 (0.37) | SLC6A2SLC6A4SLC6A3SMN1; SMN2CHRM2 | |
| SCHEMBL15274531 | 0.61 | RAB9A (0.35) | SLC6A2SLC6A4SLC6A3SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | RIPK1, RIPK4, RIPK2 | SLC6A2 4846/4885SLC6A4 4772/4885SLC6A3 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.