Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713990 | 0.92 | PSMB8 (0.31) | PSMB8PSMB5 | |
| SCHEMBL25956253 | 0.90 | KMT2A (0.30) | — | |
| SCHEMBL25818843 | 0.87 | ALDH1A1 (0.32) | PSMB8PSMB5 | |
| SCHEMBL12138348 | 0.86 | — | — | |
| SCHEMBL2263421 | 0.86 | MGLL (0.35) | MGLLPSMB8PSMB5 | |
| SCHEMBL14110324 | 0.85 | MGLL (0.31) | MGLLPSMB8PSMB5 | |
| SCHEMBL12743131 | 0.84 | ADORA3 (0.33) | MGLL | |
| SCHEMBL43576 | 0.84 | PSMB8 (0.35) | MGLLPSMB8PSMB5 | |
| SCHEMBL12015106 | 0.83 | PSMB8 (0.32) | MGLLPSMB8PSMB5 | |
| SCHEMBL26186345 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | TRANSLATE BIO, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226219-A1 | PEG LIPIDOID COMPOUNDS | LIPG, ABCB4, HDLBP | MGLL 134/4885PSMB8 1231/4885PSMB5 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.