Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165068 | 0.81 | LMNA (0.66) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL12728621 | 0.81 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL21882104 | 0.79 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL25825506 | 0.79 | CCNC (0.39) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| Hydrochloric Acid SCHEMBL263934 | 0.78 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL2494065 | 0.75 | LOXL2 (0.58) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL25820107 | 0.74 | ADK (0.38) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL2607397 | 0.74 | PSMD14 (0.68) | HTR1AADRA1DADRA1AADRA1BPSMD14 | |
| SCHEMBL24292895 | 0.74 | GABRA1 (0.38) | MAPTKDM4ELMNAGABRA1GABRB2 | |
| SCHEMBL12131703 | 0.74 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | HTR1A 3416/4885ADRA1D 3932/4885ADRA1A 3488/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | HTR1A 2664/4885ADRA1D 3449/4885ADRA1A 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.