Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010367 | 0.96 | STAT3 (0.42) | FAAHALDH1A1HPGDSTAT3GAA | |
| SCHEMBL25820812 | 0.89 | MEN1 (0.43) | FAAHALDH1A1HPGDGAAHTT | |
| SCHEMBL24010366 | 0.88 | CYP11B2 (0.40) | ALDH1A1STAT3GAAHTTCYP11B1 | |
| SCHEMBL25820804 | 0.83 | UCHL1 (0.45) | FAAHALDH1A1HPGDSTAT3GAA | |
| SCHEMBL25827157 | 0.79 | HTR2C (0.40) | STAT3GAAHTTCYP11B1CYP11B2 | |
| SCHEMBL25820814 | 0.79 | RAB9A (0.40) | ALDH1A1HPGDSMN1; SMN2TSHRMEN1 | |
| SCHEMBL24010133 | 0.79 | STAT3 (0.44) | ALDH1A1HPGDSTAT3GAAHTT | |
| SCHEMBL24010376 | 0.77 | LMNA (0.40) | ALDH1A1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL25822237 | 0.76 | LMNA (0.45) | ALDH1A1HPGDRAB9AMAPTHTR2C | |
| SCHEMBL24010132 | 0.75 | DNMT1 (0.44) | ALDH1A1GAAHTTXIAPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | FAAH 4405/4885ALDH1A1 3871/4885HPGD 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.