Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010366 | 0.94 | CYP11B2 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25820814 | 0.90 | RAB9A (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25820810 | 0.89 | FAAH (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL24010367 | 0.85 | STAT3 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25820818 | 0.85 | UCHL1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL24010376 | 0.83 | LMNA (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24010364 | 0.79 | HTR2C (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23999631 | 0.78 | CYP11B2 (0.45) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL25820817 | 0.76 | UCHL1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25821720 | 0.76 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | MEN1 1172/4885KMT2A 4131/4885ALDH1A1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.