Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010376 | 0.93 | LMNA (0.40) | RAB9ANPC1MAPTGSK3BSMN1; SMN2 | |
| SCHEMBL25820812 | 0.90 | MEN1 (0.43) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL25820817 | 0.84 | UCHL1 (0.41) | MAPTGSK3BSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24010366 | 0.84 | CYP11B2 (0.40) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25820810 | 0.79 | FAAH (0.43) | RAB9AMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24010363 | 0.78 | HTR2C (0.38) | GSK3BSMN1; SMN2ALDH1A1LMNAMAPK8 | |
| SCHEMBL23999631 | 0.75 | CYP11B2 (0.45) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25820818 | 0.75 | UCHL1 (0.42) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL24010367 | 0.75 | STAT3 (0.42) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25820801 | 0.74 | UCHL1 (0.43) | MAPTGSK3BSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | RAB9A 1255/4885NPC1 901/4885MAPT 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.