Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 9/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824044 | 0.88 | TK2 (0.42) | TK2 | |
| SCHEMBL17576576 | 0.84 | TK2 (0.53) | TK2 | |
| SCHEMBL17576579 | 0.84 | TK2 (0.53) | TK2 | |
| SCHEMBL25824050 | 0.83 | PYGM (0.50) | TK2DNPH1PYGM | |
| SCHEMBL23216894 | 0.81 | TYMP (0.48) | TK2 | |
| SCHEMBL17576592 | 0.77 | TK2 (0.48) | TK2PYGM | |
| SCHEMBL19750977 | 0.77 | TK2 (0.60) | TK2PYGM | |
| SCHEMBL9226205 | 0.76 | LMNA (0.50) | TK2PYGM | |
| SCHEMBL9226210 | 0.76 | LMNA (0.50) | TK2PYGM | |
| SCHEMBL28836967 | 0.75 | PYGM (0.62) | TK2DNPH1PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |