Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928754 | 0.82 | MAPT (0.44) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL9480445 | 0.79 | MAPT (0.48) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL8090903 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL24685877 | 0.79 | MAPT (0.44) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL25824613 | 0.77 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL1548538 | 0.77 | ALDH1A1 (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL25824636 | 0.76 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL9366846 | 0.76 | MAPT (0.77) | CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL17710410 | 0.75 | ALDH1A1 (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| Carbamic Acid SCHEMBL7402351 | 0.75 | ITGB3 (0.51) | MAPTSMN1; SMN2NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP1A2 2835/4885CYP2C9 4266/4885CYP2C19 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.