Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051745 | 0.91 | REV1 (0.64) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL8793776 | 0.82 | REV1 (0.70) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL18356020 | 0.78 | SIGMAR1 (0.51) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL30073105 | 0.78 | SIGMAR1 (0.60) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3693352 | 0.77 | SIGMAR1 (0.75) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL10383284 | 0.76 | ABCB1 (0.74) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL5449836 | 0.76 | HTR1A (0.54) | REV1SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL13726504 | 0.76 | CRHBP (0.69) | SIGMAR1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3051392 | 0.75 | CA2 (0.73) | REV1DRD4TMEM97KMT2AMAPT | |
| SCHEMBL3506177 | 0.75 | CA2 (0.73) | REV1DRD4TMEM97KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |