Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305897 | 0.84 | ELANE (0.52) | ELANEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL21662663 | 0.81 | POLB (0.46) | ELANEL3MBTL1ALDH1A1MAPK1NPC1 | |
| SCHEMBL25826624 | 0.81 | MEN1 (0.39) | ELANEL3MBTL1NPC1RAB9APRKCA | |
| SCHEMBL26271028 | 0.80 | ESR1 (0.53) | ELANEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL17803839 | 0.79 | MEN1 (0.55) | ELANEALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL20590261 | 0.78 | ALDH1A1 (0.60) | ELANEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL859603 | 0.78 | MAOB (0.49) | ELANEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL10028025 | 0.77 | RAB9A (0.57) | L3MBTL1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL13543649 | 0.76 | L3MBTL1 (0.54) | ELANEL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL13686641 | 0.76 | SMN1; SMN2 (0.54) | ELANEL3MBTL1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | ELANE 1964/4885L3MBTL1 1138/4885ALDH1A1 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.