Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948510 | 0.75 | TNKS2 (0.37) | ALDH1A1LMNAKDM4EMEN1HPGD | |
| SCHEMBL23948511 | 0.75 | CHRM2 (0.38) | KDM4ETSHR | |
| SCHEMBL23948513 | 0.75 | MEN1 (0.33) | ALDH1A1LMNATSHRMEN1HPGD | |
| SCHEMBL20570855 | 0.72 | RXFP1 (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL23948590 | 0.72 | TAAR1 (0.39) | ALDH1A1LMNAKDM4ETSHRMEN1 | |
| Acetic Acid SCHEMBL23925788 | 0.71 | ACHE (0.36) | TSHRKCNA3 | |
| SCHEMBL4860328 | 0.71 | CA2 (0.51) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL20570535 | 0.71 | HPGD (0.46) | ALDH1A1LMNATSHRHPGDKMT2A | |
| SCHEMBL9701570 | 0.70 | TDP1 (0.54) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL985442 | 0.69 | KDM4E (0.38) | ALDH1A1LMNAKDM4EUSP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | GLUL, TGM2, GLS | ALDH1A1 74/4885LMNA 2896/4885KDM4E 1011/4885 |
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | ALDH1A1 74/4885LMNA 2896/4885KDM4E 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.