Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 13/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24193842 | 0.79 | ALPL (0.48) | KLKB1HDAC6RIPK1 | |
| SCHEMBL23085471 | 0.79 | NR1H2 (0.53) | KLKB1HDAC6RIPK1 | |
| SCHEMBL3829567 | 0.74 | CA2 (0.49) | CYP2C9 | |
| SCHEMBL14367128 | 0.73 | KMT2A (0.52) | HDAC6CYP2C9 | |
| SCHEMBL24193687 | 0.71 | ALPL (0.48) | KLKB1HDAC6RIPK1 | |
| SCHEMBL24167145 | 0.70 | NR1H2 (0.53) | KLKB1HDAC6RIPK1 | |
| SCHEMBL29757046 | 0.69 | HCAR2 (0.50) | KLKB1RIPK1 | |
| SCHEMBL21889873 | 0.68 | KDM4E (0.35) | — | |
| SCHEMBL10187470 | 0.67 | LMNA (0.58) | — | |
| SCHEMBL9733928 | 0.67 | AR (0.40) | KLKB1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |