Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187470 | 0.92 | LMNA (0.58) | KMT2ALMNAHPGDALDH1A1SRD5A2 | |
| SCHEMBL14367137 | 0.89 | ACACB (0.46) | KMT2ALMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL14341653 | 0.85 | HPGD (0.46) | KMT2ALMNAHPGDALDH1A1HTT | |
| SCHEMBL14490064 | 0.84 | NOS3 (0.39) | KMT2ALMNATSHRHPGDALDH1A1 | |
| SCHEMBL21328439 | 0.84 | ACHE (0.50) | KMT2ALMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL14367132 | 0.84 | ACACB (0.43) | KMT2ALMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10587186 | 0.83 | CES2 (0.42) | KMT2ALMNATSHRHPGDALDH1A1 | |
| SCHEMBL13435233 | 0.81 | CA2 (0.52) | LMNATSHRHPGDALDH1A1HTT | |
| SCHEMBL14367060 | 0.81 | MMP12 (0.44) | KMT2AALDH1A1MAPT | |
| SCHEMBL14366630 | 0.81 | MMP12 (0.44) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070297216-A1 | SELF-ASSEMBLY OF MOLECULAR DEVICES | WILLIAM MARSH RICE UNIVERSITY (US) | 2007-12-27 | — | — | US | disclosed |