Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15383396 | 0.85 | DNM1 (0.33) | — | |
| SCHEMBL30859447 | 0.85 | DNM1 (0.44) | TSHR | |
| SCHEMBL24848020 | 0.83 | DNM1 (0.42) | TSHR | |
| SCHEMBL13044264 | 0.83 | — | — | |
| SCHEMBL3217467 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL21016075 | 0.82 | SIGMAR1 (0.44) | ALDH1A1 | |
| SCHEMBL14731785 | 0.82 | SIGMAR1 (0.44) | ALDH1A1 | |
| SCHEMBL17523776 | 0.82 | SIGMAR1 (0.44) | ALDH1A1 | |
| SCHEMBL13293939 | 0.82 | SIGMAR1 (0.32) | — | |
| SCHEMBL17523762 | 0.82 | SIGMAR1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | GLUL, TGM2, GLS | ALDH1A1 74/4885TSHR 2961/4885 |
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | ALDH1A1 74/4885TSHR 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.