SCHEMBL3217467

SCHEMBL3217467

CC(C)(C)CCN(CCC(C)(C)C)CCC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202518 0.96
SCHEMBL841608 0.87 TSHR (0.32) TSHRTDP1
SCHEMBL841648 0.87 TSHR (0.32) TSHRTDP1
SCHEMBL26380194 0.86
SCHEMBL4782094 0.85 LCK (0.34)
SCHEMBL8949497 0.85 MAPT (0.36)
SCHEMBL841265 0.83 TSHR (0.33) TSHRTDP1
SCHEMBL841870 0.83 TSHR (0.33) TSHRTDP1
SCHEMBL25018206 0.83 CA12 (0.34)
SCHEMBL841865 0.83 CA12 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN claimed
CN-110551153-A Preparation method for synthesizing tenofovir alafenamide by three-step method UNIV JIANGXI AGRICULTURAL 2019-12-10 CN claimed
US-20230312827-A1 SYNTHESIS OF NOVEL POLY(ESTER UREA)S FOR DRUG DELIVERY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-10-05 US disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2023-02-14 US disclosed
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2021-05-06 US disclosed
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN disclosed
CN-110590844-A Preparation method for synthesizing tenofovir alafenamide by two-step method 江西农业大学 2019-12-20 CN disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-20120157680-A1 IONIC LIQUID CONTAINING ALLYLSULFONATE ANION WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-21 US disclosed
EP-2463266-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE Wako Pure Chemical Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-24 US disclosed
US-20100324314-A1 PROCESS FOR PRODUCING ESTER COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-23 US disclosed
US-20100286008-A1 ADDITIVE FOR OILS AND LUBRICANT CONTAINING THE SAME KYOWA HAKKO CHEMICAL CO., LTD. (JP) 2010-11-11 US disclosed
US-20100285570-A1 FLUORIDE PROCESSING METHOD JACKSON ALEXANDER 2010-11-11 US disclosed
US-20100178242-A1 LABELLING METHODS GE HEALTHCARE LIMITED (GB) 2010-07-15 US disclosed
US-20100041916-A1 PROCESS FOR PRODUCTION OF SULFONIC ACID ESTER WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed
EP-2067770-A1 PROCESS FOR PRODUCTION OF SULFONIC ACID ESTER Wako Pure Chemical Industries, Ltd. (JP) 2009-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 TSHR 4600/4885TDP1 1469/4885
US-20100041916-A1 PROCESS FOR PRODUCTION OF SULFONIC ACID ESTER SULT1A1, SULT2A1, STS TSHR 1491/4885TDP1 3674/4885
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE ASS1, C1S, FHIT TSHR 689/4885TDP1 3074/4885
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 TSHR 4600/4885TDP1 1469/4885
US-20100286008-A1 ADDITIVE FOR OILS AND LUBRICANT CONTAINING THE SAME NR0B2, NR2E1, LBR TSHR 1586/4885TDP1 2458/4885
US-20100285570-A1 FLUORIDE PROCESSING METHOD SLCO1B1, CTSF, MEN1 TSHR 968/4885TDP1 1799/4885
US-20120157680-A1 IONIC LIQUID CONTAINING ALLYLSULFONATE ANION ATXN2L, ARL1, INPPL1 TSHR 2384/4885TDP1 3581/4885
US-20100178242-A1 LABELLING METHODS FURIN, FGF23, FGF2 TSHR 245/4885TDP1 3059/4885
US-20100324314-A1 PROCESS FOR PRODUCING ESTER COMPOUND ADH1C, ADH5, ADH1A TSHR 2452/4885TDP1 4674/4885
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 TSHR 4600/4885TDP1 1469/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 TSHR 1973/4885TDP1 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.