Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527137 | 0.78 | LMNA (0.57) | TSHRALDH1A1LMNAP2RX7RAB9A | |
| SCHEMBL9295958 | 0.74 | SLC6A2 (0.50) | TSHRALDH1A1HTTPOLBP2RX7 | |
| SCHEMBL3484200 | 0.73 | GHSR (0.44) | ALDH1A1POLBLMNAGHSR | |
| SCHEMBL8112370 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HTTPOLBP2RX7KMT2A | |
| SCHEMBL12097815 | 0.69 | TSHR (0.45) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL6357664 | 0.68 | P2RX7 (0.67) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL10946607 | 0.67 | KDM4C (0.68) | TSHRALDH1A1KDM4CNPC1GHSR | |
| SCHEMBL7265268 | 0.66 | TSHR (0.45) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL5311581 | 0.65 | TSHR (1.00) | TSHRALDH1A1POLBLMNACA1 | |
| SCHEMBL27380 | 0.65 | TSHR (1.00) | TSHRALDH1A1POLBLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036506-A1 | 5-Iodotetrazoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-05 | — | — | US | claimed |
| EP-1773125-B1 | 5-IODOTETRAZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2008-05-21 | — | — | EP | claimed |
| US-8048903-B2 | 5-iodotetrazoles | LANXESS DEUTSCHLAND GMBH (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20090036506-A1 | 5-Iodotetrazoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036506-A1 | 5-Iodotetrazoles | GPX4, CYP1A1, CYP2E1 | TSHR 1603/4885ALDH1A1 123/4885HTT 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.