Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833503 | 0.79 | GAA (0.50) | GAANPSR1MEN1KMT2ALMNA | |
| SCHEMBL5567730 | 0.75 | GAA (0.78) | GAANPSR1MEN1KMT2ALMNA | |
| SCHEMBL5806269 | 0.71 | LMNA (0.46) | GAANPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL131414 | 0.71 | L3MBTL1 (0.50) | GAAMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4524325 | 0.70 | LMNA (0.49) | NPSR1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL5569071 | 0.70 | GAA (0.69) | GAANPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5811955 | 0.70 | LMNA (0.44) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL17702628 | 0.68 | GAA (0.42) | GAALMNADPP4ALDH1A1TSHR | |
| SCHEMBL6140108 | 0.68 | GAA (0.67) | GAAMEN1KMT2ALMNADPP4 | |
| SCHEMBL17702630 | 0.67 | HSD11B1 (0.54) | GAAMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135425-A1 | INHIBITORS OF TRANSGLUTAMINASE | ASTON UNIVERSITY (GB) | 2023-07-20 | — | — | WO | disclosed |