Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833496 | 0.79 | GAA (0.52) | GAANPSR1DPP4ALDH1A1MEN1 | |
| SCHEMBL7748923 | 0.75 | ALDH1A1 (0.47) | GAANPSR1DPP4ALDH1A1MEN1 | |
| SCHEMBL11093229 | 0.75 | THRB (0.41) | GAANPSR1DPP4ALDH1A1MEN1 | |
| SCHEMBL26017392 | 0.73 | NPSR1 (0.43) | NPSR1DPP4ALDH1A1PKMTHRB | |
| SCHEMBL5567730 | 0.73 | GAA (0.78) | GAANPSR1DPP4ALDH1A1MEN1 | |
| SCHEMBL5569071 | 0.68 | GAA (0.69) | GAANPSR1DPP4ALDH1A1MEN1 | |
| SCHEMBL6901718 | 0.68 | NPSR1 (0.39) | NPSR1DPP4ALDH1A1PKMHSD11B1 | |
| SCHEMBL12705423 | 0.68 | NPSR1 (0.45) | NPSR1DPP4ALDH1A1MEN1KMT2A | |
| SCHEMBL686304 | 0.67 | NPSR1 (0.44) | NPSR1DPP4ALDH1A1MEN1KMT2A | |
| SCHEMBL5608660 | 0.67 | MEN1 (0.46) | GAANPSR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135425-A1 | INHIBITORS OF TRANSGLUTAMINASE | ASTON UNIVERSITY (GB) | 2023-07-20 | — | — | WO | disclosed |