Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716365 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| SCHEMBL1666528 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| SCHEMBL975681 | 0.76 | NCEH1 (0.53) | ALDH1A1MAPTHPGDMAOBNCEH1 | |
| SCHEMBL4276654 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| SCHEMBL27723137 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDMAOBNCEH1 | |
| SCHEMBL11122174 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| SCHEMBL27716420 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| Chrysene SCHEMBL28443586 | 0.73 | HPRT1 (0.70) | ALDH1A1MAPTHPGDMAOBHPRT1 | |
| SCHEMBL7174966 | 0.73 | WDR5 (0.56) | ALDH1A1MAPTHPGDMAOBNCEH1 | |
| SCHEMBL10484289 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDMAOBHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | ALDH1A1 323/4885MAPT 736/4885HPGD 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.