Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725752 | 0.80 | GABRA1 (0.41) | CYP2C9HIF1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3581544 | 0.80 | ATM (0.49) | CYP2C9HIF1AKDM4EHPGDL3MBTL1 | |
| SCHEMBL19660435 | 0.77 | CYP2A6 (0.44) | CYP1A2KDM4EALDH1A1HPGDPDE10A | |
| SCHEMBL21783630 | 0.75 | IDO1 (0.53) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21783631 | 0.74 | ATP4A (0.38) | CYP2C9HIF1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21783690 | 0.72 | APP (0.38) | CYP1A2CYP3A4KDM4EALDH1A1PDE10A | |
| SCHEMBL21237268 | 0.72 | CA2 (0.35) | CYP2C9HIF1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8429646 | 0.72 | CYP2C9 (0.57) | CYP2C9HIF1ACYP1A2CYP3A4KDM4E | |
| SCHEMBL29071977 | 0.70 | L3MBTL1 (0.59) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL3238496 | 0.70 | GABRA1 (0.57) | CYP1A2CYP2D6CYP2C19ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | ITGB6, ITGA6, GP6 | CYP2C9 4719/4885HIF1A 1419/4885CYP1A2 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.