Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991988 | 1.00 | RIPK1 (0.52) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8107873 | 1.00 | RIPK1 (0.52) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8742857 | 0.89 | HDAC3 (0.50) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2743315 | 0.89 | HDAC3 (0.50) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7345068 | 0.88 | FFAR1 (0.52) | LMNAALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL27820361 | 0.88 | TBXAS1 (0.55) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27585172 | 0.88 | TBXAS1 (0.55) | RIPK1LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9308449 | 0.86 | TBXAS1 (0.58) | RIPK1SMN1; SMN2MAPK1 | |
| SCHEMBL6907990 | 0.86 | TBXAS1 (0.58) | RIPK1SMN1; SMN2MAPK1 | |
| SCHEMBL6907995 | 0.86 | TBXAS1 (0.58) | RIPK1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299441-A | A kind of preparation method of ticagrelor | 于天荣 | 2018-07-20 | — | — | CN | claimed |
| CN-105777546-B | A kind of preparation method of lisinopril intermediate | 苏州引航生物科技有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-103167800-A | Ready-to-use ketorolac injection | RTU PHARMACEUTICALS LLC | 2013-06-19 | — | — | CN | claimed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2005-05-26 | — | — | US | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| US-6028224-A | Fluoxetine process from benzoylpropionic acid | SEPRACOR INC. (US) | 2000-02-22 | — | — | US | claimed |
| WO-1999067196-A1 | FLUOXETINE PROCESS FROM BENZOYLPROPIONIC ACID | SEPRACOR INC. (US) | 1999-12-29 | — | — | WO | claimed |
| US-5936124-A | Fluoxetine process from benzoylpropionic acid | SEPACOR INC. (US) | 1999-08-10 | — | — | US | claimed |
| EP-0280285-A2 | Process for making and isolating (R)-2-hydroxy 4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-31 | — | — | EP | claimed |
| JP-2142724-A | — | — | None | — | — | JP | disclosed |
| JP-2119785-A | — | — | None | — | — | JP | disclosed |
| US-12295394-B2 | Water-soluble additive composition | SUMITOMO BAKELITE CO., LTD. (JP) | 2025-05-13 | — | — | US | disclosed |
| WO-2025025244-A1 | LIGHT-EMITTING APPARATUS, PREPARATION METHOD AND ELECTRONIC DEVICE | 纳晶科技股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| EP-0329156-A1 | Process for the optical resolution of (+-)-2-hydroxy-4-phenylbutanoic acid | KURARAY CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0329156-A1 | Process for the optical resolution of (+-)-2-hydroxy-4-phenylbutanoic acid | KURARAY CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0280285-A2 | Process for making and isolating (R)-2-hydroxy 4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-31 | — | — | EP | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | GABRB1, GABRA1, GABRA5 | RIPK1 4872/4885LMNA 2279/4885ALDH1A1 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.