Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834695 | 0.81 | BACE1 (0.53) | HDAC4HDAC8ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25834697 | 0.80 | L3MBTL1 (0.37) | ALDH1A1KDM4ECYP3A4CLK4NOTUM | |
| SCHEMBL25835356 | 0.77 | HDAC4 (0.46) | HDAC4HDAC8GAANCOA1NCOA3 | |
| SCHEMBL25834699 | 0.77 | GABRP (0.34) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL25834603 | 0.76 | BACE1 (0.42) | HDAC4HDAC8GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL25835140 | 0.70 | KDM4E (0.64) | HDAC4HDAC8GAANCOA1NCOA3 | |
| SCHEMBL9727963 | 0.70 | HDAC4 (0.50) | HDAC4HDAC8GAANCOA1NCOA3 | |
| SCHEMBL25835384 | 0.70 | L3MBTL1 (0.44) | GAAALDH1A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL25834709 | 0.70 | L3MBTL1 (0.44) | GAAALDH1A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL25834786 | 0.69 | CYP2C9 (0.33) | GAAALDH1A1MEN1POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | HDAC4 3492/4885HDAC8 3205/4885GAA 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.