Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808595 | 0.84 | LMNA (0.38) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL18266512 | 0.84 | LMNA (0.38) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL19365984 | 0.83 | CYP1A2 (0.43) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL25027438 | 0.80 | TRPA1 (0.38) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL22021291 | 0.80 | NOS3 (0.38) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL16959840 | 0.80 | TRPA1 (0.38) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL20252586 | 0.78 | PDE2A (0.41) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL9461082 | 0.78 | TRPA1 (0.55) | TRPA1CYP1A2RAB9ALMNAALDH1A1 | |
| SCHEMBL19373434 | 0.77 | TRPA1 (0.35) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL19908573 | 0.77 | TRPA1 (0.35) | TRPA1CYP1A2CYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | VANDERBILT UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | OGG1, LGMN, GLO1 | TRPA1 1725/4885CYP1A2 637/4885CYP2A6 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.