Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693482 | 0.86 | SIGMAR1 (0.51) | SIGMAR1LTA4HMEN1TP53CYP1A2 | |
| SCHEMBL15186974 | 0.80 | ACHE (0.64) | SIGMAR1LTA4HMEN1KMT2AHRH3 | |
| SCHEMBL11453030 | 0.79 | POLB (0.67) | SIGMAR1MEN1KMT2ADRD2 | |
| SCHEMBL81936 | 0.79 | DRD2 (0.55) | SLC18A3DRD2CARM1PRMT6HRH3 | |
| SCHEMBL13252503 | 0.78 | LTA4H (0.58) | SIGMAR1LTA4HHRH3 | |
| SCHEMBL19557301 | 0.78 | LTA4H (0.75) | SIGMAR1LTA4HMEN1TP53CYP1A2 | |
| SCHEMBL26981197 | 0.78 | LTA4H (0.75) | SIGMAR1LTA4HMEN1TP53CYP1A2 | |
| SCHEMBL31057462 | 0.77 | LTA4H (0.61) | SIGMAR1LTA4HMEN1KMT2AHRH3 | |
| SCHEMBL17284609 | 0.77 | LTA4H (0.61) | SIGMAR1LTA4HMEN1KMT2ACARM1 | |
| SCHEMBL22878318 | 0.77 | LTA4H (0.61) | SIGMAR1LTA4HMEN1KMT2ACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793990-B1 | ANTIBACTERIAL COMPOUNDS | INFEX THERAPEUTICS LTD (GB) | 2023-07-19 | — | — | EP | disclosed |