Zinc Ion

Zinc Ion

SCHEMBL2585203

O=C(CCCCC(S)CCS)N[C@@H](CO)C(=O)[O-].O=C(CCCCC(S)CCS)N[C@@H](CO)C(=O)[O-].[NaH].[Zn+2]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 5/20 0.34
NMT2 O60551 4/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 1/20 0.34
NOD1 Q9Y239 1/20 0.32
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL2577660 0.89 KMT2A (0.33) NMT1NMT2KMT2AMEN1NOD1
Zinc Ion SCHEMBL2580359 0.88 EPHX2 (0.42) KMT2ANOD1EPHX2
Zinc Ion SCHEMBL2577508 0.86 FOLH1 (0.36) KMT2ANOD1EPHX2
Zinc Ion SCHEMBL3338508 0.86 EPHX2 (0.43) KMT2ANOD1EPHX2
Zinc Ion SCHEMBL2574083 0.85 NOD1 (0.44) KMT2AMEN1NOD1EPHX2
SCHEMBL2577356 0.84 NOD1 (0.43) NMT1NMT2KMT2AMEN1NOD1
SCHEMBL2577352 0.84 NOD1 (0.43) NMT1NMT2KMT2AMEN1NOD1
Zinc Ion SCHEMBL2580310 0.84 SLC6A5 (0.43) NMT1NMT2NOD1
SCHEMBL3276927 0.83 EPHX2 (0.46) KMT2ANOD1EPHX2
SCHEMBL4425978 0.82 EPHX2 (0.37) KMT2ANOD1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF NMT1 1190/4885NMT2 1612/4885KMT2A 1597/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 NMT1 583/4885NMT2 1009/4885KMT2A 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.