Zinc Ion

Zinc Ion

SCHEMBL2580310

NCCCC[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].NCCCC[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].[Zn+2]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 1/20 0.43
NMT1 P30419 6/20 0.40
NMT2 O60551 5/20 0.40
FOLH1 Q04609 2/20 0.37
RNPEP Q9H4A4 1/20 0.34
TLR2 O60603 1/20 0.34
NOD1 Q9Y239 3/20 0.33
CPB2 Q96IY4 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
ROCK2 O75116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL2577660 0.89 KMT2A (0.33) SLC6A5NMT1NMT2FOLH1NOD1
SCHEMBL2520684 0.86 SLC6A5 (0.56) SLC6A5NMT1NMT2FOLH1RNPEP
SCHEMBL2581261 0.86 SLC6A5 (0.56) SLC6A5NMT1NMT2FOLH1RNPEP
Zinc Ion SCHEMBL2574083 0.86 NOD1 (0.44) SLC6A5NOD1
SCHEMBL2580308 0.85 SLC6A5 (0.55) SLC6A5NMT1NMT2FOLH1RNPEP
Zinc Ion SCHEMBL2577508 0.84 FOLH1 (0.36) FOLH1NOD1
Zinc Ion SCHEMBL2585203 0.84 NMT1 (0.34) NMT1NMT2NOD1
Zinc Ion SCHEMBL3338508 0.84 EPHX2 (0.43) NOD1
Zinc Ion SCHEMBL2580359 0.83 EPHX2 (0.42) NOD1
Zinc Ion SCHEMBL2574899 0.82 FNTA (0.46) RNPEPNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF SLC6A5 2176/4885NMT1 1190/4885NMT2 1612/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 SLC6A5 1510/4885NMT1 583/4885NMT2 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.