Zinc Ion

Zinc Ion

SCHEMBL2580359

O=C([O-])C[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].[NaH].[Zn+2]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.42
CPT2 P23786 1/20 0.34
CPT1A P50416 1/20 0.34
CPT1B Q92523 1/20 0.34
NOD1 Q9Y239 4/20 0.33
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL3338508 0.99 EPHX2 (0.43) EPHX2CPT2CPT1ACPT1BNOD1
SCHEMBL3276927 0.96 EPHX2 (0.46) EPHX2CPT2CPT1ACPT1BNOD1
Zinc Ion SCHEMBL2585203 0.88 NMT1 (0.34) EPHX2NOD1KMT2A
Zinc Ion SCHEMBL2577660 0.87 KMT2A (0.33) EPHX2NOD1KMT2A
SCHEMBL4425978 0.86 EPHX2 (0.37) EPHX2NOD1KMT2A
Zinc Ion SCHEMBL2577508 0.85 FOLH1 (0.36) EPHX2NOD1KMT2A
Zinc Ion SCHEMBL2574083 0.84 NOD1 (0.44) EPHX2CPT2CPT1ACPT1BNOD1
Zinc Ion SCHEMBL2580310 0.83 SLC6A5 (0.43) NOD1
Zinc Ion SCHEMBL2582837 0.81 FAAH (0.40) CPT2CPT1ACPT1BNOD1KMT2A
Zinc Ion SCHEMBL2574899 0.81 FNTA (0.46) EPHX2NOD1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF EPHX2 4410/4885CPT2 3334/4885CPT1A 4240/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 EPHX2 3181/4885CPT2 3083/4885CPT1A 3519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.