Zinc Ion

Zinc Ion

SCHEMBL2574083

CCCC[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].CCCC[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].[NaH].[Zn+2]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 7/20 0.44
SLC6A5 Q9Y345 2/20 0.39
EPHX2 P34913 1/20 0.38
PLA2G2C Q5R387 1/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
FAAH O00519 2/20 0.38
MAPK1 P28482 1/20 0.38
CPT2 P23786 1/20 0.35
CPT1A P50416 1/20 0.35
CPT1B Q92523 1/20 0.35
CA2 P00918 1/20 0.35
DNM1 Q05193 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL2577508 0.86 FOLH1 (0.36) NOD1EPHX2PLA2G2CKMT2A
Zinc Ion SCHEMBL2580310 0.86 SLC6A5 (0.43) NOD1SLC6A5
SCHEMBL2583437 0.85 NOD1 (0.61) NOD1SLC6A5EPHX2PLA2G2CFAAH
SCHEMBL2583434 0.85 NOD1 (0.61) NOD1SLC6A5EPHX2PLA2G2CFAAH
Zinc Ion SCHEMBL2585203 0.85 NMT1 (0.34) NOD1EPHX2KMT2AMEN1
Zinc Ion SCHEMBL2577660 0.85 KMT2A (0.33) NOD1SLC6A5EPHX2KMT2AMEN1
Zinc Ion SCHEMBL2580359 0.84 EPHX2 (0.42) NOD1EPHX2KMT2ACPT2CPT1A
Zinc Ion SCHEMBL2574899 0.84 FNTA (0.46) NOD1EPHX2KMT2A
Zinc Ion SCHEMBL3338508 0.83 EPHX2 (0.43) NOD1EPHX2KMT2ACPT2CPT1A
Zinc Ion SCHEMBL2582837 0.81 FAAH (0.40) NOD1SLC6A5PLA2G2CKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF NOD1 4616/4885SLC6A5 2176/4885EPHX2 4410/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 NOD1 4460/4885SLC6A5 1510/4885EPHX2 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.