Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111132 | 0.77 | ACLY (0.40) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL5820739 | 0.77 | ALDH1A1 (0.34) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL1049551 | 0.70 | CYP2C19 (0.44) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL1643768 | 0.67 | CYP2C19 (0.46) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL11798809 | 0.64 | CYP2C19 (0.42) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL28527107 | 0.63 | ACLY (0.53) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL11466997 | 0.63 | MEN1 (0.34) | ALDH1A1CYP2D6TSHRCYP2C19SLC6A2 | |
| Succinic Acid SCHEMBL7712865 | 0.62 | LMNA (0.41) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL12458905 | 0.62 | ACLY (0.39) | ACLYCPT2ALDH1A1CYP2D6TSHR | |
| SCHEMBL1020093 | 0.62 | ALDH1A1 (0.42) | ACLYCPT2ALDH1A1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563760-A2 | BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES | WYSIS Technology Foundation, Inc. (US) | 2013-03-06 | — | — | EP | claimed |
| WO-2011139887-A2 | BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES | WYSIS TECHNOLOGY FOUNDATION, INC. (US) | 2011-11-10 | — | — | WO | claimed |
| US-20110269903-A1 | BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES | WYSIS TECHNOLOGY FOUNDATION, INC. (US) | 2011-11-03 | — | — | US | claimed |
| EP-3336076-A1 | BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES | WiSys Technology Foundation, Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269903-A1 | BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES | QSOX1, MTX1, MSRB3 | ACLY 2761/4885CPT2 3232/4885ALDH1A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.